Principles and Applications of NMR Spectroscopy

By Prof. H S Atreya | IISc Bangalore

Learners enrolled: 1282

The objective of the course is to teach the basic aspects of nuclear magnetic resonance (NMR) spectroscopy, which is an important analytical tool in chemical and pharmaceutial industry for structural characterization of molecules. The topics to be covered will include one-dimensional NMR, Chemical shifts, J-coupling, Interpretation of 1D NMR spectrum, Basics of 2D NMR, Different 2D NMR experiments and their application/interpretation, Application of 2D NMR for assignment of molecules and peptides.

INTENDED AUDIENCE : Students of M. Sc and Ph. D

PREREQUISITES :Should have studied Chemistry at undergraduate level and Mathematics at least up to 12th Standard

INDUSTRY SUPPORT : All pharmaceutical companies (e.g., Reddy's laboratories, CIPLA, Sun Pharma) and R &D laboratories like Hindustan Unilever, Biotech companies (Biocon)

Summary

Course Status :	Completed
Course Type :	Elective
Duration :	8 weeks
Category :	Biological Sciences & Bioengineering
Credit Points :	2
Level :	Postgraduate
Start Date :	27 Jan 2020
End Date :	20 Mar 2020
Enrollment Ends :	15 Feb 2021
Exam Date :	29 Mar 2020 IST

Note: This exam date is subjected to change based on seat availability. You can check final exam date on your hall ticket.

Page Visits

Course layout

Week 1: Introduction to NMR spectroscopy
Week 2: Chemical shifts and J-coupling
Week 3: One-dimensional proton NMR
Week 4: One dimensional NMR of X-nuclei (13C, 15N, 31P and 19F)
Week 5: Homonuclear 2D NMR
Week 6: Heteronucler 2D NMR
Week 7: Structure determination of molecules
Week 8: Advanced topics (Solvent suppression, Drug Discovery, DOSY)

Books and references

1. Basic One and Two Dimensional NMR: by Horst Fiebrolin 
2. NMR Spectroscopy Explained: by Neil Jacobsen
3. Understanding NMR spectroscopy: by James Keeler
4. Introduction to Spectroscopy: by Pavia et al.

Instructor bio

Prof. H S Atreya

IISc Bangalore

Prof. H. S. Atreya is an Associate Professor at the Indian Institute of Science. He has nearly 20 years of experience in the area of NMR spectroscopy. He has authored approximately 75 peer review publications, edited one book and has two US patents. Research interests include development and application of new magnetic resonance methodologies for studying structure, function and dynamics of biomolecules.

Course certificate

• The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
• The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
• Date and Time of Exams: 29th March 2020, Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
• Registration url: Announcements will be made when the registration form is open for registrations.
• The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
• Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

CRITERIA TO GET A CERTIFICATE:
• Average assignment score = 25% of average of best 6 assignments out of the total 8 assignments given in the course.
• Exam score = 75% of the proctored certification exam score out of 100
• Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75.
• If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.
• Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Kanpur. It will be e-verifiable at nptel.ac.in/noc.
• Only the e-certificate will be made available. Hard copies will not be dispatched.

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