X
X
X

X
Swayam Central

Physics of Biological Systems

By Prof. Mithun Mitra   |   IIT Bombay
The application of physical principles to biological systems is an exciting and rapidly evolving feld of research. Methods of equilibrium and non-equilibrium statistical physics, stochastic processes, non-linear dynamics and polymer physics, among others have helped understand the guiding principles of a variety of biological processes. In this course,we will attempt to provide an introduction to the physics of biological systems using theoretical tools, with examples from diverse areas of biology such as pattern formation, low Reynolds number fows, cytoskeleton and motors and transport in cells, gene expression and chromatin organisation, among others.



INTENDED AUDIENCE : All Engineering students
PREREQUISITES : Statistical Mechanics (Preferred, not a hard prerequisite)
INDUSTRY SUPPORT : NA

Learners enrolled: 305

SUMMARY

Course Status : Upcoming
Course Type : Elective
Duration : 12 weeks
Start Date : 27 Jan 2020
End Date : 17 Apr 2020
Exam Date : 25 Apr 2020
Enrollment Ends : 03 Feb 2020
Category :
  • Physics
  • Level : Undergraduate/Postgraduate
    This is an AICTE approved FDP course

    COURSE LAYOUT

    Week 1 : Introduction to Biophysics, Spatial and temporal scales
    Week 2 : Random walks and diffusion in biology, FRAP, cell signaling
    Week 3 : Diffusion and capture processes, Mean capture times 
    Week 4 : Fluid flows in biology, viscosity and Navier Stokes equation 
    Week 5 : Life at low Reynolds number, Scallop theorem and bacterial flagella 
    Week 6 : Equilibrium Statistical Mechanics: Energy, entropy, free energy 
    Week 7 : Two-state systems, cooperative binding, Haemoglobin
    Week 8 : Polymers and biopolymers, Entropic elasticity, persistence length
    Week 9 : Force spectroscopy, HP model of protein folding, Chromosome models
    Week 10 : Life in crowded environments, Depletion forces
    Week 11 : Biological dynamics and rate equations, motors and filaments
    Week 12 : Pattern formation in bology, Reaction-diffusion systems

    BOOKS AND REFERENCES

    Physical Biology of the Cell, Rob Phillips, Jane Kondev, Julie Theriot,
    Hernan Garcia (CRC Press)
    Biological Physics, Philip Nelson (W.H. Freeman)
    Mathematical Models in Biology, Elizabeth Allman, John Rhodes
    (Cambridge University Press)
    Random Walks in Biology, Howard Berg (Princeton University Press)

    INSTRUCTOR BIO

    Prof. Mithun Mitra

    IIT Bombay
    I am a theoretical physicist with a training in statistical mechanics and soft condensed matter physics. My research focuses on understanding the physics of living systems, using both theoretical and simulation methods. In particular, some of the topics I am interested in include transport inside cells, the packaging of chromosomes in nuclei, and the physical principles underlying morphogenesis and growth of embryos.

    COURSE CERTIFICATE

    • The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
    • The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
    Date and Time of Exams: 25th April 2020, Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
    • Registration url: Announcements will be made when the registration form is open for registrations.
    • The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
    • Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

    CRITERIA TO GET A CERTIFICATE:
    • Average assignment score = 25% of average of best 8 assignments out of the total 12 assignments given in the course. 
    • Exam score = 75% of the proctored certification exam score out of 100
    • Final score = Average assignment score + Exam score

    YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. 
    • If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.
    • Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Bombay. It will be e-verifiable at nptel.ac.in/noc.
    • Only the e-certificate will be made available. Hard copies will not be dispatched.

    DOWNLOAD APP

    FOLLOW US