Industrial Pharmacy-I

By Dr Ajay Semalty | HNB Garhwal University (A Central University) Srinagar Garhwal (Uttarakhand)

Learners enrolled: 5070

Course Credit- 04

After the successful first run in 2019, we are back with the first Pharmacy SWAYAM MOOC of country. My self Dr Ajay Semalty along with my team members welcome you in the course.

Do you want to learn the basics of Industrial Pharmacy with practical approach and vibrant environment? Come join our course.

The course is one of the papers of Fifth semester of B. Pharmacy syllabi approved by Pharmacy Council of India (PCI) and is adopted uniformly by all the pharmacy institutions and Universities throughout the country. All other learners who want to learn the basics of industrial pharmacy can get the vital benefit out of this course.

Objectives

The course has been designed with the aim that after completing this course, you should be able

To identify and practice Dosage forms; and their manufacturing techniques
To practice all the related and practical aspect of dosage form development
To formulate and evaluate solid, liquid and semisolid dosage forms
To correlate the theoretical knowledge with professional and practical need of pharmaceutical industry

Target Learners:
B. Pharm/ M Pharm/ Ph D Pharmacy students; researchers, Pharmacy faculty members/ Pharma Industry Personnel; the students of B Sc/ M Sc Chemistry/ Pharm. Chemistry/ biotechnology and other allied disciplines who aspire for the jobs in Pharma Industry or research.

Pharmacy students will get the 4 credits after successful completion of the course (and proctored exam). And the industry personals who are not from pharmacy background may enrich their knowledge with this course. The course is very suitable for all the aspirants of jobs in Pharma Industry even if they are not from Pharmacy background.

Course has been designed with the USPs
Easy language, to-the-point coverage of topics, pictorial/graphical, animated and Audio Video knowledge store with the standards needed by the Pharma industry. The course is one of the pioneer MOOC in pharmaceutical sciences developed with the expert advice from academic and industry experts.

The Team IP

Dr Ajay Semalty
(Course Coordinator & Subject Matter Expert)

Dr Mona Semalty
(Co-Course Coordinator & Subject Matter Expert)

Mr Lokesh Adhikari
(Subject Matter Expert)

Production:
EMRC Roorkee

Summary

Course Status :	Completed
Course Type :	Core
Duration :	12 weeks
Category :	Multidisciplinary
Credit Points :	4
Level :	Undergraduate/Postgraduate
Start Date :	07 Sep 2020
End Date :	30 Nov 2020
Enrollment Ends :	14 Oct 2020
Exam Date :

Page Visits

Course layout

WEEK: 12
MODULES 40
Week 1 Preformulation I

Preformulation I: Physical form (crystal & amorphous),

Preformulation I: polymorphism, particle size, shape

Preformulation I:, solubility profile (pKa, pH)

Preformulation I: Partition coefficient, flow properties

Week 2 Preformulation II

Preformulation II: Hydrolysis, oxidation, reduction

Preformulation II: Racemisation,

Preformulation II: Dissolution, permeability & BCS classification

Preformulation II: Polymerization

Week 3 Tablets

Tablets: Introduction, classification of tablets. Formulation/preparing of tablets, granulation methods.

Tablets: Compression and processing problems. Equipment and tablet tooling, Tablet defects.

Tablets: Tablet coating: Types, coating materials, formulation of coating composition, methods of coating, equipments employed and defects in coating

Tablets: QC of tablets: apparatus, methods, graphical presentations, official and unofficial tests.

Week 4 Liquid Orals

Liquid orals: Formulation and manufacturing of solution, syrups and elixirs, Filling and packaging

Liquid orals: Emulsions: I

Liquid orals: Emulsion II

Liquid orals: Suspensions: Formulation, evaluation

Week 5 Parenterals I

Parenterals I: Introduction, Preformulation of parenterals

Parenterals I: Formulation of Parenterals

Week 6 Parenterals I

Parenterals I: Types of Parenteral preparation

Parenterals I: Lay out and Production facilities

Week 7 Parenterals II

Parenterals II: Pyrogens and pyrogenisity

Parenterals II: Quality control of parenterals

Week 8 Capsules

Capsules: Introduction, Advantages, Disadvantages, Capsule Production, hard Gelatin capsules

Capsules: Methods of filling capsules, Soft Gelatin Capsules

Capsules: Formulation Consideration, Production of soft gelatin capsules, Non-gelatin soft capsules

Capsules: Evaluation of commercial capsules

Week 9 Pellets and Ophthalmic Preparations

Pellets: Introduction, formulation, pelletization process, equipment needed

Ophthalmic Preparations: Introduction, absorption through eye, formulation considerations

Ophthalmic Preparations: formulation of eye drops, lotion, ointments

Ophthalmic Preparations: Methods of preparation; labeling, containers Evaluation

Week 10 Pharmaceutical Aerosols

Pharmaceutical Aerosols: Definitions, Advantages, Limitation, Uses

Pharmaceutical Aerosols: Components of aerosols

Pharmaceutical Aerosols: Components and systems of aerosols

Pharmaceutical Aerosols: inhalers and Evaluation of Aerosols

Week 11 Cosmetics

Cosmetics: Introduction, absorption through skin, types of cosmetic preparations, Formulation of tooth pastes

Cosmetics: Formulation of lipsticks, shampoos, hair dyes

Cosmetics: Formulation of cold cream and vanishing cream, sunscreens

Week 12 Packaging Materials Science

Packaging Materials Science: Materials used for packaging of pharmaceutical products,

Packaging Materials Science: Factors influencing choice of containers Legal and official requirements, Stability aspects,

Packaging Materials Science: Quality control tests of packaging materials

Books and references

IP/USP/BP
Semalty et al. Essentials of Pharmaceutical Technology, II edn 2018, reprint 2019, Pharma med Press, Hyderabad
Niazi SK, Handbook of Preformulation, Informa Health Care, 2007
Aulton ME (ED), Pharmaceutics: The science of Dosage form design, II edn, Churchill Livingstone, London, 2002.
Banker GS & Rhodes T, Modern Pharmaceutics, CRC Press.
Lachman L/Lieberman HA, Kanig JL, The Theory And Practice Of Industrial Pharmacy,4E (2013).
Qiu Y, Chang Y and Zhang GZ (Exe. Eds), Developing solid oral dosage forms: Pharmaceutical theory and practice, Elsevier, 2009.
Gibson M. (Ed), Pharmaceutical preformulation and formulation: a practical guide from candidate drug selection to commercial dosage form, II edn, Informa Healthcare.
Qiu Y, Chang Y and Zhang GZ (Exe. Eds), Developing solid oral dosage forms: Pharmaceutical theory and practice, Elsevier, 2009
Dressman JB, Karmer J, Pharmaceutical Dissolution Testing, 2005, Taylor & Francis, NY.
Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems. Philadelphia: Lipincott Williams and Wilkins.
Augsburger LL, Hoag SW (Eds), Pharmaceutical Dosage Forms: Tablets, Volume 1, III Edn, Informa healthcare, 2008

Instructor bio

Dr Ajay Semalty

HNB Garhwal University (A Central University) Srinagar Garhwal (Uttarakhand)

M. Pharm. (Pharmaceutics), MBA (Operations Management); Ph. D., PDF Meijo University, Japan; Academic and research experience of 16 Yrs and 1 yr Industrial Experience; Completed 10 research projects funded by various agencies; Successfully developed and run two SWAYAM MOOCs (Academic Writing and Industrial Pharmacy I) with 80 hrs of Teaching Learning Materials including more than 40 hrs of video lectures; Contributed 4 e-modules for ARPIT course of GJU Science & technology Hisar; Published 74 papers, 6 books (including the best seller "Essentials of Pharmaceutical Technology" by Pharma Med Press), 2 patents (01 granted). He has presented papers in more than 100 conferences; Highly cited researcher of the field (h index 23); Awarded Daiko Foundation Post-Doctoral Research Fellowship and invited by Meijo University, Nagoya, Japan as visiting scientist for research for FY 2011-12; Awarded with the prestigious national Research Award by UGC, New Delhi and Young Scientist Award of the year 2007 by Uttarakhand Council of Science & Technology (UCOST); Expert reviewer of Iceland Research Foundation Iceland; Israel Science Foundationn (ISF) Israel and Scientific Expert (REPRISE) for Ministry of Institution and University Research (MIUR), Italy. Delivered more than 40 invited lectures (on Open Educational Resources (OERs), Academic writing, Nanoparticle research, Research methodology, Research ethics, Software in research, MOOC, blended/ flipped learning, research proposal writing, academic integrity, plagiarism etc.) in various training programs in Faculty Development Centers (FDCs), Human Resource Development Centers (HRDCs) and other institutions. He is member of The Asian Council of Science Editors, APTI and IPA; Editorial Board Member and Peer reviewer of various national and International reputed journals; The University SWAYAM Coordinator of Garhwal University; Supervised 20 M. Pharm research projects; Research interest include cyclodextrin and lipid complexes, Small angle neutron scattering (SANS), nanoparticles, natural products for drug delivery like obesity and hair loss.