|Course Status :||Ongoing|
|Course Type :||Core|
|Duration :||15 weeks|
|Start Date :||06 Jan 2020|
|End Date :||18 Apr 2020|
|Exam Date :||09 May 2020|
|Enrollment Ends :||08 Mar 2020|
"This course is very great and is helpful not only for students but also for all chemistry professors. This course is the best platform for all organic chemistry learners. The language is very easy. So that, each and every student can understand all the concepts easily. Discussion forum is also a best platform for us to ask any query about any concept.
Thank you very much sir for excellent teaching, clearing every concept in organic chemistry from basic and giving assignments to us. Keep it up sir.
Also,thanks to SWAYAM for conducting such type of course for all chemistry learners." ---- Ketaki, One of the topper from the course July-2019.
"The classes are very explanatory and very useful for the PG students and also for the faculty members. I really appreciate the efforts taken by Balaji sir. " ---Seethalakshmi S "The course content was so relevant and insightful that every individual would definitely benefit hugely from it for their career in chemistry. The classes are very vivid, crystal clear and knowledgeable. I am very fortunate to be part of this course." ---- Ramakrishna S "Professor Balaji did splendid job and did lots of efforts. Its been 15 days to the course have started and I am taking it right now. This course is beneficial to all as the professor took the course from basics to advance, this make learning very easy & he is very responsive which makes it very convenient." ----- Simran K "very good nd well qualified professors.
for solving gate, net questions, dis course iz useful. thanku for efforts of all professors". ---- Anonymous Syllabus Week 1
Introduction to stereochemistry
Conformational analysis of open chain systems
Conformational analysis of cyclic systems Symmetry elements, Point group analysis Stereochemical conventions
Stereogenicity, Topicity ORD and CD, Axial halo ketone rule, Octant Rule
Stereochemical reactions Reactions involving stereo centres Crams Rule, Felkin-Anh model, Prelog rules
Aromaticity, Aromatic stabilization energy, Hückel MO, Musulin-Frost diagram Polycyclic aromatic hydrocarbon (PAH), Polyacenes, Annulene
Aromatic Electrophilic substitutions Aromatic Nucleophilic substitutions Ipso-cine-tele substitution
Reaction dynamics, Hammond postulate Linear free energy relationship, Hammett equation
Yukawa Tsuno equation, Swain-Lupton equation, Grunwald–Winstein equation, Taft equation Curtin-Hammett principle, Winstein-Holness equation
Carbocation, Part 1: Generation, Structure and Geometry
Carbocation, Part 2: Stabilisation of carbocation, Reactions
Carbocation, Rearrangement 1: No Change in carbon skeleton, Change in carbon skeleton
Carbocation, Rearrangement 2: involvement of other electron deficient terminus, Anchimeric assistance
Carbanions: pKa and its significance
Carbanions: Hard and Soft Acid and Base principle
Carbanions: Structure, Formation, Stability, Reactivity
Carbanion reactions: Acyl Anions, Benzoin condensation, Umpolung-inversion of reactivity
Free radical 1: Formation, Structure, Stability
Free radical 2: Stability, Reactivity Free radical 3: Reactions: Addition, atom abstraction, disproportionation, cyclisation
Free radical 4: Reactions: Fenton, Kolbe, Bouveault-Blanc, Giese, Hofmann-Loffler, Birch, Barton-McCombie, Sandmeyer, Barton decarboxylation
Carbene, Nitrene: Generation, Structure, Reactivity
Carbonyl addition reaction Enol and enolate formation and reactionsEnamines formation and reactions
Enol ethers formation and reactions, Mukaiyama-Aldol reaction Sharpless epoxidation, Click reaction, Diels-Alder reaction- Scope and mechanism
March's Advanced Organic Chemistry Reactions, Mechanisms and Structure 5th Ed. Michael B. Smith, Jerry March, John Wiley & Sons, Inc., 2001.
F. A. Carey: Organic Chemistry, 5th Ed., McGraw-Hill, 2004.
Peter Sykes, A Guidebook to Mechanism in Organic Chemistry, 6th Ed, John Wiley and Sons. Inc, New York, 1986.
J. Clayden, N. Greeves, S. Warren, Organic Chemistry, 2nd Ed., Oxford University Press, New Delhi, 2012.
F. A. Carey and R. J. Sundberg, Advanced Organic Chemistry, Part A & B, 5th Ed., Springer, New York, 2007.
Thomas H. Lowry and Kathleen Schueller Richardson, Mechanism and theory in Organic Chemistry, Harper& Row, Publishers, 1976.
Paula Yurkanis Bruice, Organic Chemistry, 4th Ed. Prentice Hall, 2003.
Arvi Rauk, Orbital Interaction Theory of Organic Chemistry, 2nd Ed., John Wiley & Sons, Inc., 2001.
D. Nasipuri, Stereochemistry of organic compounds, Principles and Applications, 3rd Ed. New Age International Publishers, 2018.
P. S. Kalsi, Stereochemistry: Conformation and Mechanism, 9th Ed, New Age International (P) Ltd., 2017.
Ernest L. Eliel, Samuel H. Wilen, Stereochemistry of Organic Compounds, Wiley India Ed, 2008.
I. L. Finar, Organic Chemistry, Volume 2: Stereochemistry and The Chemistry of Natural Products, Chapter 2, 5th Ed, Pearson Education India, 1956.