|Course Status :||Ongoing|
|Course Type :||Core|
|Duration :||15 weeks|
|Start Date :||15 Jul 2019|
|End Date :||30 Oct 2019|
|Exam Date :||10 Nov 2019|
|Enrollment Ends :||11 Sep 2019|
Introduction to stereochemistry Conformational analysis of open chain systems Conformational analysis of cyclic systems
Symmetry elements, Point group analysis Stereochemical conventions
Stereogenicity, Topicity ORD and CD, Axial halo ketone rule, Octant Rule
Stereochemical reactions Reactions involving stereo centres Crams Rule, Felkin-Anh model, Prelog rules
Aromaticity, Aromatic stabilization energy, Hückel MO, Musulin-Frost diagram Polycyclic aromatic hydrocarbon (PAH), Polyacenes, Annulene
Aromatic Electrophilic substitutions Aromatic Nucleophilic substitutions Ipso-cine-tele substitution
Reaction dynamics, Hammond postulate Linear free energy relationship, Hammett equation
Yukawa Tsuno equation, Swain-Lupton equation, Grunwald–Winstein equation, Taft equation Curtin-Hammett principle, Winstein-Holness equation
Carbocation, Part 1: Generation, Structure and Geometry
Carbocation, Part 2: Stabilisation of carbocation, Reactions
Carbocation, Rearrangement 1: No Change in carbon skeleton, Change in carbon skeleton
Carbocation, Rearrangement 2: involvement of other electron deficient terminus, Anchimeric assistance
Carbanions: pKa and its significance
Carbanions: Hard and Soft Acid and Base principle
Carbanions: Structure, Formation, Stability, Reactivity
Carbanion reactions: Acyl Anions, Benzoin condensation, Umpolung-inversion of reactivity
Free radical 1: Formation, Structure, Stability
Free radical 2: Stability, Reactivity
Free radical 3: Reactions
Carbene, Nitrene: Generation, Structure, Reactivity
Carbonyl addition reaction
Carbonyl addition reaction
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J. Clayden, N. Greeves, S. Warren, Organic Chemistry, 2nd Ed., Oxford University Press, New Delhi, 2012.
F. A. Carey and R. J. Sundberg, Advanced Organic Chemistry, Part A & B, 5th Ed., Springer, New York, 2007.
Thomas H. Lowry and Kathleen Schueller Richardson, Mechanism and theory in Organic Chemistry, Harper& Row, Publishers, 1976.
Paula Yurkanis Bruice, Organic Chemistry, 4th Ed. Prentice Hall, 2003.
Arvi Rauk, Orbital Interaction Theory of Organic Chemistry, 2nd Ed., John Wiley & Sons, Inc., 2001.
D. Nasipuri, Stereochemistry of organic compounds, Principles and Applications, 3rd Ed. New Age International Publishers, 2018.
P. S. Kalsi, Stereochemistry: Conformation and Mechanism, 9th Ed, New Age International (P) Ltd., 2017.
Ernest L. Eliel, Samuel H. Wilen, Stereochemistry of Organic Compounds, Wiley India Ed, 2008.
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