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Swayam Central

Biomicrofluidics

By Prof. Tapas Kumar Maiti and Prof. Suman Chakraborty   |   IIT Kharagpur

Biomicrofluidics is an interdisciplinary domain that fuses microfluidics/ nanofluidics with the science of living systems, having outstanding applications in multifarious domain ranging from medical diagnostics to targeted drug delivery. It is an emerging field of research which today, is not only helping in the understanding of diseases from an engineering perspective, but also aiding in the development of inexpensive, portable, diagnostic platforms that can predict whether a person is carrying a disease, even from a small drop of body fluid, at the remotest of locations. Biomicrofluidics, primarily rests on the pillars of cellular and molecular biology and microscale fluid mechanics. The understanding of any subject in its entirety is often incomplete without knowledge and tools derived from other disciplines. This course is thus intended to give engineers an overview of the biology of the cell and at the same time, biologists, a lucid understanding of fluidic transport processes at the microscale. Eventually, this course aims to demonstrate how the amalgamation of Biology and Engineering is leading to a growing body of knowledge about progression of diseases and the development of simpler replacements of tedious biological assay procedures including affordable point-of-care diagnostic kits.

INTENDED AUDIENCE:
Any engineering/Biology discipline
PREREQUISITES: None



SUMMARY

Course Status : Upcoming
Course Type : Elective
Duration : 4 weeks
Start Date : 26 Aug 2019
End Date : 20 Sep 2019
Exam Date : 17 Nov 2019
Category :
  • Biological Sciences & Bioengineering
  • Level : Undergraduate
    This is an AICTE approved FDP course

    COURSE LAYOUT



    Week 1 :  Introduction to Biomicrofluidics
                    
    Engineers’ guide to the cell 
                    Fluidics in living systems and mechanobiology 
                    Pressure driven flows 

    Week 2 :  Surface tension driven flows
                     
    Modulating surface tension
                     
    Lab on a CD
                     
    Introduction to Electrokinetics

    Week 3 :  Microfluidic cell culture 
                     
    On-chip cellular assay techniques
                     
    Microfluidics for understanding biology
     
     Week 4 :  Organ-on-a-chip 
                     
    Lab-on-a-chip for genetic analysis
                     Microfluidic technology for monoclonal antibody production
     

    BOOKS AND REFERENCES

    Nil

    INSTRUCTOR BIO


    Prof. Tapas Kumar Maiti is a Professor in the Biotechnology Department of the Indian Institute of Technology (IIT) Kharagpur, India, since 1995. He is a biochemist by training, working on natural anti-cancer lectins, immunomodulatory mushroom glucans, tissue engineering, biomicrofluidics-based understanding of cancer progression, as well as development of microfluidic chip-based cancer-screening devices and drug-testing models. He teaches the courses Biochemistry, Down Stream Processing, Immunology, Metabolic Engineering, Enzyme Technology at the undergraduate level and Immunotechnology, Bioseparation and Bioprocess Technology at the post-graduate level. He received the UNESCO-SGM-IUMS Fellowship in 2003-2004 for visiting Foreign Laboratory. He has 210+ publications in International Journals, 75+ published abstracts in Conference proceedings, 3 book chapters, 1 awarded patent and 4 filed patents.


    Prof. Suman Chakraborty is a Professor in the Mechanical Engineering Department of the Indian Institute of Technology (IIT) Kharagpur, India, and the Institute Chair Professor. He is also currently the Head, School of Medical Science and Technology at IIT Kharagpur. He has offered a significant number of video courses through the NPTEL programme. These courses include: Introduction to Fluid Mechanics and Fluids Engineering, Computational Fluid Dynamics, and Microfluidics. He has also taught in an online programme (under NMEICT) titled “Talk to 10 Thousand Teachers”. He has also taught live modular courses in the International Summer Winter Term and Knowledge Dissemination Programme. He has research interests in the area of Microfluidics and Micro/Nano scale transport processes, including their theoretical, computational, and experimental modeling, encompassing the underlying fundamentals as well as bio-medical, bio-technological, chip cooling, and energy related applications. As recognition of his research, he has been awarded the Santi Swarup Bhatnagar Prize in the year 2013. He has also been elected as a Fellow of the Indian National Science Academy (INSA), Fellow of the Indian National Academy of Science (FNASc), Fellow of the Indian National Academy of Engineering (FNAE), Fellow of the American Physical Society (APS), Fellow of the Royal Society of Chemistry (RSC), Fellow of the American Society of Mechanical Engineers (ASME), recipient of the Indo-US Research Fellowship, Scopus Young Scientist Award for high citation of his research in scientific/technical Journals, and Young Scientist/ Young Engineer Awards from various National Academies of Science and Engineering. He has further been an Alexander von Humboldt Fellow and a Visiting Professor at the Stanford University. He has 370+ International Journal publications. 

    COURSE CERTIFICATE

    • The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
    • The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
    • Date and Time of Exams: 17 November 2019, Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
    • Registration url: Announcements will be made when the registration form is open for registrations.
    • The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
    • Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

    CRITERIA TO GET A CERTIFICATE
    • Average assignment score = 25% of average of best 3 assignments out of the total 4 assignments given in the course. 
    • Exam score = 75% of the proctored certification exam score out of 100
    • Final score = Average assignment score + Exam score

    YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75
    • If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.
    • Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Kharagpur. It will be e-verifiable at nptel.ac.in/noc.
    • Only the e-certificate will be made available. Hard copies are being discontinued from July 2019 semester and will not be dispatched

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