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Swayam Central

Metals In Biology

By Dr. Debabrata Maiti   |   IIT Bombay
Metals are the vital component of any biosystem. Starting from transporting biochemicals to catalyzing biochemical transformations, almost every process requires presence of a metal center. In order to understand these processes knowledge of specific functions carried out by these metals are necessary. This course will be helpful to understand the fundamental properties of the metals present in biosystems and mechanism of their action.

INTENDED AUDIENCE : Chemistry, Biochemistry Students/faculty
PREREQUISITES :          Nil

SUMMARY

Course Status : Upcoming
Course Type : Core
Duration : 8 weeks
Start Date : 29 Jul 2019
End Date : 20 Sep 2019
Exam Date : 29 Sep 2019
Category :
  • Maths and Sciences
  • Level : Postgraduate
    This is an AICTE approved FDP course

    COURSE LAYOUT

    Week 1 :
    Lecture 1: Introduction
    Lecture 2,3: Distribution of metals in biology
    Lecture 4,5: Metal storage in body
    Week 2 :
    Lecture 6,7: Regulation of metal concentration
    Lecture 8,9 : Metal folding of biopolymers
    Lecture 10: Electron Transfer protiens
    Week 3 :
    Lecture 11: Electron Transfer protiens
    Lecture 12,13,14: Molecular oxygen carriers
    Lecture 15: Hydrolytic and related enzymes
    Week 4 :
    Lecture 16: Hydrolytic and related enzymes
    Lecture 17,18: Hydroxylases
    Lecture 19,20: Hydrogenases and bioorganometallic chemistry
    Week 5 :
    Lecture 21,22: Active site model systems
    Lecture 23: Nitrogenase
    Lecture 24: Photosynthesis
    Lecture 25: Co-enzymes
    Week 6 :
    Lecture 26: Co-enzymes
    Lecture 27,28: Effect of metal concentration
    Lecture 29,30: Signaling 
    Week 7 :
    Lecture 31,32: Metal toxicity
    Lecture 33,34: Metals in medicine
    Lecture 35: Metalloneurochemistry:zinc, NO, others
    Week 8 :
    Lecture 36: Metalloneurochemistry: zinc, NO, others
    Lecture 37,38: Metals, microbes, and the immune system
    Lecture 39,40: Metalloprotein engineering: convert protein function 


    BOOKS AND REFERENCES

    Principles of Bioinorganic Chemistry- Stephen J. Lippard

    INSTRUCTOR BIO



    I am Dr. Debabrata Maiti, Associate Professor at IIT Bombay. I have completed my PhD from Johns Hopkins University with Prof. Kenneth D. Karlin in bioinorganic chemistry. Then I moved to MIT where I did my Post-doctoral research with Prof. Steven Buchwald. I have started independent carrier at IIT Bombay in 2011 and since then involved actively in teaching bio-inorganic chemistry and organometallic chemistry. Our group is also active in research areas of bio-inorganic chemistry and C-H activation.

    COURSE CERTIFICATE

    • The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
    • The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
    • Date and Time of Exams: 29th September 2019 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
    • Registration url: Announcements will be made when the registration form is open for registrations.
    • The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
    • Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

    CRITERIA TO GET A CERTIFICATE
    • Average assignment score = 25% of average of best 6 assignments out of the total 8 assignments given in the course.
    • Exam score = 75% of the proctored certification exam score out of 100
    • Final score = Average assignment score + Exam score

    YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75
    • If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.
    • Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Bombay. It will be e-verifiable at nptel.ac.in/noc.
    • Only the e-certificate will be made available. Hard copies are being discontinued from July 2019 semester and will not be dispatched

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