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Swayam Central

Virology

By Dr. RAGHAVENDRA M.P.   |   Maharani’s Science College for Women, Mysuru-570 005
Virology provides information on viruses, which are associated with several emerging infectious diseases in both animals and plants. Most of the viral diseases are not curable and developing treatment strategy for these diseases is the real tough challenge for the researchers. It is possible only when all the information on its structure, replication, mode of transmission and especially methods of cultivating viruses are easily available. This will pay the way for understanding pathogenicity and targets for drug development. Prevention is better than cure suits better with the viral infections. Hence this course is developed to provide knowledge on nature, host and replication of different group of viruses, spread and management of viral diseases. The course also provides information on beneficial aspects of virus, especially its use in medicine and agriculture. The syllabus is designed keeping in mind the recent developments in virology and will be useful to all those who want to learn and update their knowledge on viruses.

Learners enrolled: 1485

SUMMARY

Course Status : Upcoming
Course Type : Elective
Duration : 12 weeks
Start Date : 06 Jul 2020
End Date : 29 Nov 2020
Exam Date :
Enrollment Ends : 30 Sep 2020
Category :
  • Biological Sciences & Bioengineering
  • Level : Undergraduate

    COURSE LAYOUT


    Weekly Plan

     

    Weeks

    Day

    Weekly Lecture Topics

    First Week

    Day 1

    Discovery, nature, origin and evolutionary importance of viruses

    Day 2

    Structure of Viruses

    Day 3

    Isolation, purification and cultivation of viruses

    Day 4

    Viral taxonomy: Classification and nomenclature of different groups of viruses

    Day 5

    ●       MCQ           ●       Assignments

     

    Second Week

    Day 1

    Diversity, classification and one step multiplication curve

    Day 2

    Lytic and lysogenic phages

    Day 3

    Regulation of transcription in lambda phage

    Day 4

    Phage phenotypes, phenotype mixing and phage therapy

    Day 5

    ●       MCQ     ●       Assignments

     

    Third Week

    Day 1

    Principal events involved in replication: Adsorption, penetration and uncoating.

    Day 2

    Viral nucleic acid and protein synthesis

    Day 3

    Intracellular trafficking, assembly, maturation and release

    Day 4

    Host response to viral infection

    Day 5

    ●       MCQ       ●       Assignments

     

    Fourth Week

    Day 1

    TMV and BBTV

    Day 2

    Herpes, Polio and Influenza virus

    Day 3

    SV40 and Adeno Virus, Poxviruses

    Day 4

    Hepatitis and Retroviruses

    Day 5

    ●       MCQ       ●       Assignments

    Fifth Week

    Day 1

    Visualization and enumeration of virus particles

    Day 2

    Physical and biological methods of detection of viruses

    Day 3

    Immunological and molecular methods detection of viruses

    Day 4

    Characterization of viral product expressed in the infected cells

    Day 5

    ●       MCQ     ●       Assignments

    Sixth  Week

    Day 1

    General methods of propagation of plant viruses

    Day 2

    Purification of plant viruses using centrifugation, chromatography and electrophoresis techniques

    Day 3

    Methods employed in identification of plant viruses

    Day 4

    Viruses as biopesticides

    Day 5

    ●       MCQ      ●       Assignments

     

    Seventh  Week

    Day 1

    Common cold, SARS, Influenza

    Day 2

    Measles, Mumps, Rubella, Human papilloma

    Day 3

    Herpes, Polio, Rabies, Small pox

    Day 4

    HIV, Hepatitis, Dengue, Yellow fever

    Day 5

    ●       Quizzes   ●       Assignments  ●       Paragraph and essay questions

     

    Eighth Week

    Day 1

    Introduction to oncogenic viruses

    Day 2

    Concepts of oncogenes and proto-oncogenes

    Day 3

    Understanding human carcinogenesis by using tumor viruses as experimental tools

    Day 4

    Prevention and treatment of virus induced cancer

    Day 5

    ●       MCQ   ●       Assignments

     

    Ninth  Week

    Day 1

    Host specific and nonspecific defense mechanisms involved in resistance to and recovery from virus infections

    Day 2

    Role of interferon in viral infections

    Day 3

    Viral Chemotherapy: Nucleoside analogs, reverse transcriptase inhibitors, protease inhibitors

    Day 4

    History of vaccines especially smallpox and polio. New methods: subunit vaccines, anti-idiotype and DNA vaccines

    Day 5

    ●       MCQ     ●       Assignments

    Tenth Week

    Day 1

    Use of viral vectors in cloning and expression

    Day 2

    Gene therapy and Phage display

    Day 3

    Emerging and re emerging viruses

    Day 4

    Viruses and future

    Day 5

    ●       MCQ        ●       Assignments

     

    Eleventh   Week

    Day 1

    Exam preparation and assessment of assignments

    Day 2

    Day 3

    Day 4

    Day 5

    Twelfth   Week

    Day 1

    Assessment at the end of the course, which comprises of 40% of Online or In-term assessment and 60% Proctored end term exam.

    Day 2

    Day 3

    Day 4

    Day 5

     

     


    BOOKS AND REFERENCES

    1. Carter J.B. and Saunders V.A. 2007. Virology: Principles and applications. John Wiley & Sons Ltd.
    2. Cheng R.H. and Miyamura T. 2008. Structure based study of viral replication. World Scientific Co. Pvt. Ltd.
    3. Dimmock N.J., Easton A.J. and Leppard K.N. 2007. 6th edition. Introduction to modern virology. Blackwell Publication.
    4. Wagner E.K., Hewlett M.J., Bloom D.C. and Camerini D. Basic virology. 3rd edition. Blackwell Publication. 

    INSTRUCTOR BIO

    Dr. RAGHAVENDRA M.P.

    Maharani’s Science College for Women, Mysuru-570 005
    Dr. Raghavendra M.P. is presently working as a Assistant Professor in PG Department of Microbiology, Maharani’s Science College for Women, Mysuru. He obtained M.Sc. and Ph.D. in Microbiology from University of Mysore during 1999 and 2007 respectively. He has cleared CSIR-UGC-NET in life sciences (2001), ICMR-JRF competitive exam in 2000 and recipient of CSIR-SRF during 2003-2006. He is a recipient of ISCA young scientist award in 2010 and of Dr. Anne Kuriakose endowment best teacher in India award in 2016 with cash prize Rs. 10,000=00.

    He has published 40 research papers with 1150 citations, with an h index of 15 and i10 index of 18. He has authored 15 book chapters published by CABI, Springer, Elsevier and other publishers. He has more than 16 years of teaching experience at postgraduate level.

    COURSE CERTIFICATE

    Assessment/Assignment marks will be considered for Internal Marks and will carry 30 percent for overall Result.

    End Term Exam- will have 100 questions and will carry 70 percent of  overall Result.

    *All students, who obtain 40% marks in in-course assessment and 40% marks in end-term proctored exam separately, will be eligible for certificate and credit transfer.

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